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Made for all that follows a craniotomy. One solution, endless possibilities.

Beyond the skull

INTRA is a Class IIb medical device, certified under Directive 93/42/EEC since 2021, designed to enable advanced transcranial ultrasound imaging and therapies.

Manufactured from a biocompatible material, it is available in three standard sizes and can be adapted in the sterile field using common surgical instruments.

Key advantages

Compared to other transparent cranial prostheses, INTRA offers:

  • Superior sonolucency compared to traditional materials

  • High ultrasonic energy transmission (up to 88%) for clearer, more accurate imaging

  • Minimal distortion, outperforming materials such as PMMA

  • Low porosity for optimal acoustic window performance

Clinical applications

INTRA is suitable for any post-craniotomy application, including trauma, stroke, epilepsy, tumors, neuromodulation, neurodegenerative and movement disorders, Chiari malformation decompression, hydrocephalus management, and bypass patency assessment.

Diagnostic
Ultrasound over CT/MRI for follow-up imaging

  • No radiation, lower costs, faster imaging

  • Bedside, clinic, and home monitoring

  • Convenient surveillance for outpatient care

  • Dynamic assessment in different positions

  • Easy follow-up, fewer emergency room visits

Therapeutic
Ultrasound-guided treatments

  • Focused ultrasound for neurosurgery and neuro-oncology

  • Non-invasive blood–brain barrier opening for targeted, effective drug delivery

  • Potential therapies for neurodegenerative and movement disorders

© 2035 by Intelligenza Trasparente S.r.l.

P.IVA: 10049930968

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